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Chemical Structure : NCC-149
Catalog No.: PC-60134Not For Human Use, Lab Use Only.
NCC-149 is a potent and selective HDAC8 inhibitor with IC50 of 70 nM.
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NCC-149 is a potent and selective HDAC8 inhibitor with IC50 of 70 nM.
NCC-149 displays high selectivity over major HDACs (HDAC1: IC50 38 uM, HDAC2 >100 uM, HDAC4: IC50: 44 uM,HDAC6: IC50 2.4 uM).
| M.Wt | 326.374 | |
| Formula | C16H14N4O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Suzuki T, et al. ChemMedChem. 2014 Mar;9(3):657-64.
2. Suzuki T, et al. PLoS One. 2013 Jul 16;8(7):e68669.
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