NCS-382 | GHBR inhibitor | Probechem Biochemicals

Chemical Structure : NCS-382

NCS-382 (NCS382)

Catalog No.: PC-49436Not For Human Use, Lab Use Only.

NCS-382 is a a gamma-hydroxybutyrate receptor (GHBR) antagonist, brain-penetrating high nanomolar-affinity ligand selective for the CaMKIIα hub domain, possesses antagonistic properties.

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Biological Activity

NCS-382 is a a gamma-hydroxybutyrate receptor (GHBR) antagonist, brain-penetrating high nanomolar-affinity ligand selective for the CaMKIIα hub domain, possesses antagonistic properties.

Physicochemical Properties

M.Wt	218.252
Formula	C13H14O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-2-(5-Hydroxy-5,7,8,9-tetrahydro-6H-benzo[7]annulen-6-ylidene)acetic acid

References

1. Schmidt C, et al. Eur J Pharmacol. 1991 Oct 22;203(3):393-7.

2. Maitre M, et al. J Pharmacol Exp Ther. 1990 Nov;255(2):657-63.

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NCS-382 (NCS382)

Biological Activity

Physicochemical Properties

References

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