NDC-1171 | SERCA activator | Probechem Biochemicals

Chemical Structure : NDC-1171

NDC-1171 (NDC1171)

Catalog No.: PC-26650Not For Human Use, Lab Use Only.

NDC-1171 is a potent, selective positive allosteric modulator/ activator of sarcoplasmic/endoplasmic reticulum calcium ATPase (SERCA) pump, improves SERCA-mediated Ca2+ cycling, attenuates cardiac functional decline in mouse model of Duchenne muscular dystrophy (DMD).

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Biological Activity

NDC-1171 is a potent, selective, orally available positive allosteric modulator/ activator of sarcoplasmic/endoplasmic reticulum calcium ATPase (SERCA) pump, improves SERCA-mediated Ca2+ cycling, attenuates cardiac functional decline in mouse model of Duchenne muscular dystrophy (DMD).

Physicochemical Properties

M.Wt	310.78
Formula	C18H15ClN2O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-chloro-4-methyl-N-(2-methylquinolin-8-yl)benzamide

References

1. Narra N, et al. bioRxiv [Preprint]. 2026 Mar 9:2026.03.05.709950.

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NDC-1171 (NDC1171)

Biological Activity

Physicochemical Properties

References

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