NDM-552 | PBP2 inhibitor | Probechem Biochemicals

Chemical Structure : NDM-552

NDM-552 (NDM552)

Catalog No.: PC-28393Not For Human Use, Lab Use Only.

NDM-552 is a Gram-positive selective antibacterial agent that potentially targets penicillin-binding protein 2 (PBP2)-associated cell wall biosynthesis, exhibits activity against Gram-positive pathogens including S. aureus, Enterococcus faecium, and Staphylococcus epidermidis with MIC of 1-2 ug/mL.

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Biological Activity

Physicochemical Properties

M.Wt	420.35
Formula	C20H19Cl2N3OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-chloro-N-(2-chloro-4-(4-methylpiperazin-1-yl)phenyl)benzo[b]thiophene-2-carboxamide

References

1. Stefaniak MA, et al. Antibiotics (Basel). 2026 Aug 25;15(9):826.

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NDM-552 (NDM552)

Biological Activity

Physicochemical Properties

References

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