Chemical Structure : NGP-555
CAS No.: 1304630-27-0
Catalog No.: PC-22498Not For Human Use, Lab Use Only.
NGP-555 (NGP555) is a potent, selective γ-secretase modulator with Aβ42 IC50 of 10 nM.
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NGP-555 (NGP555) is a potent, selective γ-secretase modulator with Aβ42 IC50 of 10 nM.
M.Wt | 406.52 | |
Formula | C23H23FN4S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
N-(5-Ethyl-2,4-dimethylphenyl)-4-[3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl]-2-thiazolamine |
1. Pettersson M, et al. J Med Chem. 2024 Jun 7. doi: 10.1021/acs.jmedchem.4c00580.
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