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NGP-555

Chemical Structure : NGP-555

CAS No.: 1304630-27-0

NGP-555 (NGP555)

Catalog No.: PC-22498Not For Human Use, Lab Use Only.

NGP-555 (NGP555) is a potent, selective γ-secretase modulator with Aβ42 IC50 of 10 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

NGP-555 (NGP555) is a potent, selective γ-secretase modulator with Aβ42 IC50 of 10 nM.

Physicochemical Properties

M.Wt 406.52
Formula C23H23FN4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(5-Ethyl-2,4-dimethylphenyl)-4-[3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl]-2-thiazolamine

References

1. Pettersson M, et al. J Med Chem. 2024 Jun 7. doi: 10.1021/acs.jmedchem.4c00580.

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