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Chemical Structure : NITD-349
CAS No.: 1473450-62-2
Catalog No.: PC-61755Not For Human Use, Lab Use Only.
NITD-349 is a novel, orally bioavailable mycobacterial membrane protein Large 3 (MmpL3) inhibitor with MIC of 23 nM against M tuberculosis H37Rv.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $68 | In stock | |
| 10 mg | $98 | In stock | |
| 25 mg | $168 | In stock | |
| 50 mg | $258 | In stock | |
| 100 mg | Get quote |
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NITD-349 is a novel, orally bioavailable mycobacterial membrane protein Large 3 (MmpL3) inhibitor with MIC of 23 nM against M tuberculosis H37Rv.
NITD-349 shows potent activity against both drug-sensitive and multidrug-resistant clinical isolates of Mtb.
NITD-349 demonstrates effectivity in treating both acute and chronic Mtb infections in mouse efficacy models.
| M.Wt | 306.36 | |
| Formula | C17H20F2N2O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N-(4,4-dimethylcyclohexyl)-4,6-difluoro-1H-indole-2-carboxamide |
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1. Rao SP, et al. Sci Transl Med. 2013 Dec 4;5(214):214ra168.
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