Chemical Structure : NK250
Catalog No.: PC-26810Not For Human Use, Lab Use Only.
NK250 is a potent, selective, Cullin-Ring-E3 ligase (CRL)-dependent USP7 PROTAC degrader with DC50 of 4 nM in MV4-11 cells (24 h).
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NK250 is a potent, selective, Cullin-Ring-E3 ligase (CRL)-dependent USP7 PROTAC degrader with DC50 of 4 nM in MV4-11 cells (24 h).
NK250 (250 nM) induces complete degradation of USP7 with PROTAC NK250 in Panc89 cells.
| M.Wt | 1136.43 | |
| Formula | C62H77N11O8S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Nikolas Klink, et al. bioRxiv doi: https://doi.org/10.1101/2025.07.01.662351

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