NMA39

Chemical Structure : NMA39

Catalog No.: PC-26964Not For Human Use, Lab Use Only.

NMA39 is a small-molecule Nur77 modulator (SPR Kd=563 nM) that disrupts the Nur77-Cep192 interaction, induces mitotic arrest and death in tumor cells, also blocks Nur77-PLK1 interaction during mitosis, mimicking the effect of Cdk1 inhibition.

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Biological Activity

Physicochemical Properties

M.Wt	493.69
Formula	C31H43NO4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(2R,4aS,6aS,9S,12bR,14aS,14bR)-9-methoxy-N,2,4a,6a,9,12b,14a-heptamethyl-10,11-dioxo-1,2,3,4,4a,5,6,6a,9,10,11,12b,13,14,14a,14b-hexadecahydropicene-2-carboxamide

References

1. Guobin Xie, et al. Cell Death Dis. 2026 Jun 3. doi: 10.1038/s41419-026-08870-3.

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NMA39

Biological Activity

Physicochemical Properties

References

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