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Chemical Structure : NNC-0640
CAS No.: 307986-98-7
Catalog No.: PC-70023Not For Human Use, Lab Use Only.
NNC-0640 (NNC 0640, NNC0640) is a potent, selective glucagon receptor (GCGR) negative allosteric modulator with IC50 of 69.2 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $98 | In stock | |
| 10 mg | $148 | In stock | |
| 25 mg | $258 | In stock | |
| 50 mg | $428 | In stock | |
| 100 mg | Get quote |
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NNC-0640 (NNC 0640, NNC0640) is a potent, selective glucagon receptor (GCGR) negative allosteric modulator with IC50 of 69.2 nM.
NNC-0640 also inhibits a penel of mutant GCGRs with IC50 of 100-700 nM.
| M.Wt | 573.672 | |
| Formula | C29H31N7O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
4-((1-(4-cyclohexylphenyl)-3-(3-(methylsulfonyl)phenyl)ureido)methyl)-N-(1H-tetrazol-5-yl)benzamide |
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1. Jazayeri A, et al. Nature. 2016 May 12;533(7602):274-7.
2. Zhang H, et al. Nature. 2017 Jun 8;546(7657):259-264.
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