NP1192 | NAT10 PROTAC | Probechem Biochemicals

Chemical Structure : NP1192

NP1192 (NP-1192)

Catalog No.: PC-25951Not For Human Use, Lab Use Only.

NP1192 is a highly effective PROTAC degrader targeting NAT10, promotes NAT10 KD and inhibits ac4C modification, facilitates NAT10 degradation through the ubiquitin-proteasome system (UPS).

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Biological Activity

NP1192 is a highly effective PROTAC degrader targeting NAT10, promotes NAT10 KD and inhibits ac4C modification, facilitates NAT10 degradation through the ubiquitin-proteasome system (UPS).

Physicochemical Properties

M.Wt	734.88
Formula	C39H42N8O5S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzonitrile, 4-[2-[2-cyclopentylidene-1-[7-[4-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-1-piperazinyl]-7-oxoheptyl]hydrazinyl]-4-thiazolyl]-

References

1. Ao K, et al. ACS Cent Sci. 2025 Sep 16;11(11):2087-2107.

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NP1192 (NP-1192)

Biological Activity

Physicochemical Properties

References

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