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NPD4928

Chemical Structure : NPD4928

CAS No.: 956965-61-0

NPD4928 (NPD 4928)

Catalog No.: PC-72763Not For Human Use, Lab Use Only.

NPD4928 (NPD 4928) is a small molecule that enhances ferroptosis via inhibition of ferroptosis suppressor protein 1 (FSP1).

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Biological Activity

NPD4928 (NPD 4928) is a small molecule that enhances ferroptosis via inhibition of ferroptosis suppressor protein 1 (FSP1).
NPD4928 enhanced the sensitivity of various cancer cells to GPX4 inhibitor RSL3.

Physicochemical Properties

M.Wt 504.583
Formula C29H32N2O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(2-(5-methoxy-1H-indol-3-yl)ethyl)-2-((3,4,8,8-tetramethyl-2-oxo-9,10-dihydro-2H,8H-pyrano[2,3-f]chromen-5-yl)oxy)acetamide

References

1. Hiromasa Yoshioka, et al. ACS Chem Biol. 2022 Feb 7.

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