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Chemical Structure : NPL-4011
Catalog No.: PC-49500Not For Human Use, Lab Use Only.
NPL-4011 is a specific small molecule inhibitor of PDZ domain of human Dvl1 (Dvl1-PDZ) with KD vaule of 34.5 uM in NMR titration experiments.
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NPL-4011 is a specific small molecule inhibitor of PDZ domain of human Dvl1 (Dvl1-PDZ) with KD vaule of 34.5 uM in NMR titration experiments.
NPL-4011 is a stronger inhibitor than CalBioChem-322338 (KD=954 uM).
NPL-4011 (100 uM) demonstrated cell proliferation inhibition of BT-20 triple negative breast cancer cell.
| M.Wt | 582.61 | |
| Formula | C33H30N2O8 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Hori K, et al. Front Pharmacol. 2018 Sep 5;9:983.
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