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Chemical Structure : NPY5RA-972
CAS No.: 439861-56-0
Catalog No.: PC-38604Not For Human Use, Lab Use Only.
NPY5RA-972 is a potent, highly selective, orally active, and CNS-penetrant neuropeptide Y5 receptor (NPY5) antagonist with IC50 of 3.1 nM, highly selective with respect to Y1, Y2, and Y4 receptors.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $198 | In stock | |
| 10 mg | $298 | In stock | |
| 25 mg | $498 | In stock | |
| 100 mg | Get quote |
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NPY5RA-972 is a potent, highly selective, orally active, and CNS-penetrant neuropeptide Y5 receptor (NPY5) antagonist with IC50 of 3.1 nM, highly selective with respect to Y1, Y2, and Y4 receptors.
NPY5RA-972 is a highly potent Y5 antagonist in vivo, but chronic administration of NPY5RA-972 (10 mg/kg twice daily) had no effect on food intake or body weight in either free-feeding Wistar rats or dietary obese rats..
| M.Wt | 351.44 | |
| Formula | C21H25N3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N-[4-Methyl-9-(1-methylethyl)-9H-carbazol-3-yl]-4-morpholinecarboxamide |
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1. Michael H Block, et al. J Med Chem. 2002 Aug 1;45(16):3509-23.
2. Turnbull AV, et al. Diabetes. 2002 Aug;51(8):2441-9.
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