Catalog No.: PC-38604Not For Human Use, Lab Use Only.
NPY5RA-972 is a potent, highly selective, orally active, and CNS-penetrant neuropeptide Y5 receptor (NPY5) antagonist with IC50 of 3.1 nM, highly selective with respect to Y1, Y2, and Y4 receptors.
NPY5RA-972 is a potent, highly selective, orally active, and CNS-penetrant neuropeptide Y5 receptor (NPY5) antagonist with IC50 of 3.1 nM, highly selective with respect to Y1, Y2, and Y4 receptors.
NPY5RA-972 is a highly potent Y5 antagonist in vivo, but chronic administration of NPY5RA-972 (10 mg/kg twice daily) had no effect on food intake or body weight in either free-feeding Wistar rats or dietary obese rats..
