Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : NS15370
Catalog No.: PC-60229Not For Human Use, Lab Use Only.
NS15370 is a highly potent positive modulator of Kv7 channels with EC50 of 100 nM (Kv7.2-Kv7.5).
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
NS15370 is a highly potent positive modulator of Kv7 channels with EC50 of 100 nM (Kv7.2-Kv7.5).
NS15370 hyperpolarizes and increases spike frequency adaptation of hippocampal CA1 neurons in brain slices.
NS15370 reduces MK-801-induced hyperactivity in models of partial epilepsia.
| M.Wt | 442.442 | |
| Formula | C23H21F3N4O2 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Dalby-Brown W, et al. Eur J Pharmacol. 2013 Jun 5;709(1-3):52-63.
2. Jepps TA, et al. Br J Pharmacol. 2014 Oct;171(19):4413-24.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
