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Chemical Structure : NSC 141562
Catalog No.: PC-60435Not For Human Use, Lab Use Only.
A potent small-molecule inhibitor of the MIR155 host gene/miR-155 axis.
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A potent small-molecule inhibitor of the MIR155 host gene/miR-155 axis; strongly inhibits mature miR-155 generation in a timedependent manner in U87 and primary GBM cells, reduces the proliferation, migration and invasion, increases the expression of PCDH9 and PCDH7, decreases the expression of mesenchymal transition-associated markers, N-cadherin, vimentin, MMP9 and β-catenin.
| M.Wt | 376.302 | |
| Formula | C17H22BrN5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Wu X, et al. Neuro Oncol. 2017 Sep 1;19(9):1195-1205.
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