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Chemical Structure : NSC23925B
Catalog No.: PC-62666Not For Human Use, Lab Use Only.
NSC23925B is a small molecule agent that reverses MDR in cancer cells, reverses MDR in several drug-resistant cell lines expressing P-gp.
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NSC23925B is a small molecule agent that reverses MDR in cancer cells, reverses MDR in several drug-resistant cell lines expressing P-gp.
NSC23925B resensitizes cancer cell lines to paclitaxel, doxorubicin, mitoxantrone, etc.
NSC23925B significantly enhances in vivo antitumor activity of paclitaxel in MDR xenograft models, without increasing the level of paclitaxel toxicity.
| M.Wt | 421.362 | |
| Formula | C22H26Cl2N2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Duan Z, et al. J Med Chem. 2012 Apr 12;55(7):3113-21.
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