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NSC602247

Chemical Structure : NSC602247

CAS No.: 131555-87-8

NSC602247

Catalog No.: PC-26735Not For Human Use, Lab Use Only.

NSC602247 is a small molecule inhibitor of human chloride intracellular channel 1 (HsCLIC1), binds to HsCLIC1 with micromolar affinity (6 uM), NSC602247 impairs HT29 cell growth and inhibits HsCLIC1 membrane translocation.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

NSC602247 is a small molecule inhibitor of human chloride intracellular channel 1 (HsCLIC1), binds to HsCLIC1 with micromolar affinity (6 uM), NSC602247 impairs HT29 cell growth and inhibits HsCLIC1 membrane translocation.

Physicochemical Properties

M.Wt 308.34
Formula C17H16N4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4,4'-((6-methylpyrimidine-2,4-diyl)bis(azanediyl))diphenol

References

1. Shobhan Kuila, et al. J Biol Chem. 2026 May 6:113113.

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