Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : NSC622608
CAS No.: 2593254-90-9
Catalog No.: PC-38145Not For Human Use, Lab Use Only.
NSC622608 (NSC 622608) is the first small-molecule ligand for immune checkpoint VISTA with IC50 of 4.8 uM in FRET assay.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $188 | In stock | |
| 25 mg | $298 | In stock | |
| 50 mg | $468 | In stock | |
| 100 mg | Get quote | ||
| 200 mg | Get quote | ||
| 1 g | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
NSC622608 (NSC 622608) is the first small-molecule ligand for immune checkpoint VISTA with IC50 of 4.8 uM in FRET assay.
NSC622608 disrupts VISTA-VSIG-3 interaction with IC50 of 9.7 uM in ELISA assays.
SPR screening confirmed binding of NSC622608 to VISTA ECD with an estimated KD of 6.2 uM.
| M.Wt | 322.239 | |
| Formula | C9H12BrN3OS2 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(Z)-3-((furan-2-ylmethyl)imino)-N,N-dimethyl-3H-1,2,4-dithiazol-5-amine hydrobromide |
|
1. Moustafa T Gabr, et al. J Am Chem Soc. 2020 Sep 23;142(38):16194-16198.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
