NSD2-LDD

Chemical Structure : NSD2-LDD

Catalog No.: PC-27158Not For Human Use, Lab Use Only.

NSD2-LDD is a cereblon-recruiting and PWWP1-mediated ligand directed degrader (LDD) of histone methyltransferase NSD2, selectively and potently eliminates full length and PWWP1 domain containing NSD2 protein isoforms, induces global loss of H3K36me2 and reverses the oncogenic program of t(4;14) multiple myeloma.

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Biological Activity

Physicochemical Properties

M.Wt
Formula
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES

References

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NSD2-LDD

Biological Activity

Physicochemical Properties

References

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