NTQ2494 | Axl inhibitor | Probechem Biochemicals

Chemical Structure : NTQ2494

Catalog No.: PC-26794Not For Human Use, Lab Use Only.

NTQ2494 is a potent seletive, and orally bioavailable inhibitor of AXL kinase with IC50 of 4.89 nM.

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Biological Activity

NTQ2494 is a potent seletive, and orally bioavailable inhibitor of AXL kinase with IC50 of 4.89 nM.

M.Wt	554.07
Formula	C29H37ClN5O2P
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-(2-((5-chloro-2-((7-(pyrrolidin-1-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)amino)pyrimidin-4-yl)amino)-5-(methoxymethyl)phenyl)dimethylphosphine oxide

1. Lin-Lin Zhang, et al. Eur J Med Chem. 2026 May 17:315:118955.