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NTQ2494

Chemical Structure : NTQ2494

CAS No.: 2750027-59-7

NTQ2494 (NTQ-2494)

Catalog No.: PC-26794Not For Human Use, Lab Use Only.

NTQ2494 is a potent and orally bioavailable inhibitor of AXL kinase.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

NTQ2494 is a potent and orally bioavailable inhibitor of AXL kinase.

Physicochemical Properties

M.Wt 554.07
Formula C29H37ClN5O2P
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-(2-((5-chloro-2-((7-(pyrrolidin-1-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)amino)pyrimidin-4-yl)amino)-5-(methoxymethyl)phenyl)dimethylphosphine oxide

References

1. Lin-Lin Zhang, et al. Eur J Med Chem. 2026 May 17:315:118955.

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