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NTRC-739

Chemical Structure : NTRC-739

CAS No.: 1612188-96-1

NTRC-739 (NTRC739)

Catalog No.: PC-22265Not For Human Use, Lab Use Only.

NTRC-739 is a selective nonpeptide neurotensin receptor type 2 (NTS2/NTSR2) partial agonist with EC50 of 12 nM, binding Ki of 153 nM, displays no activity against NST1.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

NTRC-739 is a selective nonpeptide neurotensin receptor type 2 (NTS2/NTSR2) partial agonist with EC50 of 12 nM, binding Ki of 153 nM, displays no activity against NST1.

Physicochemical Properties

M.Wt 437.47
Formula C24H24FN3O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-({[1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)cyclohexane carboxylic acid

References

1. Thomas JB, et al. J Med Chem. 2014 Jun 26;57(12):5318-32.

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