NTRC-739 | NTSR2 agonist | Probechem Biochemicals

Chemical Structure : NTRC-739

NTRC-739 (NTRC739)

Catalog No.: PC-22265Not For Human Use, Lab Use Only.

NTRC-739 is a selective nonpeptide neurotensin receptor type 2 (NTS2/NTSR2) partial agonist with EC50 of 12 nM, binding Ki of 153 nM, displays no activity against NST1.

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Biological Activity

NTRC-739 is a selective nonpeptide neurotensin receptor type 2 (NTS2/NTSR2) partial agonist with EC50 of 12 nM, binding Ki of 153 nM, displays no activity against NST1.

Physicochemical Properties

M.Wt	437.47
Formula	C24H24FN3O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-({[1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)cyclohexane carboxylic acid

References

1. Thomas JB, et al. J Med Chem. 2014 Jun 26;57(12):5318-32.

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NTRC-739 (NTRC739)

Biological Activity

Physicochemical Properties

References

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