NVS-CRF38 |CAS:1207258-55-6 Probechem Biochemicals

Chemical Structure : NVS-CRF38

Catalog No.: PC-42988Not For Human Use, Lab Use Only.

NVS-CRF38 is a potent, selective, orally bioavailable corticotropin-releasing factor receptor 1 (CRF1) antagonist with IC50 of 70 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

NVS-CRF38 is a potent, selective, orally bioavailable corticotropin-releasing factor receptor 1 (CRF1) antagonist with IC50 of 70 nM.

M.Wt	351.4023
Formula	C19H21N5O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Pyrazolo[5,1-b]oxazole, 7-(3,5-dimethyl-1H-1,2,4-triazol-1-yl)-3-(4-methoxy-2-methylphenyl)-2,6-dimethyl-

1. Stringer RA, et al. Xenobiotica. 2014 Oct;44(10):902-12.

2. Stringer RA, et al. Drug Metab Dispos. 2014 May;42(5):954-62.

3. Stringer RA, et al. Drug Metab Dispos. 2014 Jul;42(7):1117-24.