Catalog No.: PC-21441Not For Human Use, Lab Use Only.
NXC736 (Vonifimod, SLB736) hydrochloride is a selective functional antagonist for type 4 sphingosine-1-phosphate receptor (S1PR4, S1P4 receptor), has immunomodulatory and anti-fibrotic effects.
NXC736 (Vonifimod, SLB736) hydrochloride is a selective functional antagonist for type 4 sphingosine-1-phosphate receptor (S1PR4, S1P4 receptor), has immunomodulatory and anti-fibrotic effects.
NXC736 (SLB736) selectively binds to S1P1 and S1P4.
NXC736 (SLB736) inhibits inflammasome activation by interfering with the NLRP3-ASC-cleaved caspase-1 interaction, thereby reducing the expression of IL-1β and blocking the fibrotic pathway.
NXC736 (SLB736) is a potent therapeutic agent against radiation-induced lung fibrosis (RILF).
