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Chemical Structure : NYX-1492
Catalog No.: PC-21266Not For Human Use, Lab Use Only.
NYX-1492 is a small molecule PCSK9 inhibitor, blocks PCSK9 binding with the LDLR, attenuates inflammation in vascular cells and tissue-engineered blood vessels (TEBVs).
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NYX-1492 is a small molecule PCSK9 inhibitor, blocks PCSK9 binding with the LDLR, attenuates inflammation in vascular cells and tissue-engineered blood vessels (TEBVs).
NYX-1492 reduces monocyte adhesion in P+ TEBVs with evidence of lowering secretion of VCAM-1 and TNF-α.
| M.Wt | 581.59 | |
| Formula | C31H28F5N5O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Jounghyun H Lee, et al. APL Bioeng. 2023 Oct 16;7(4):046103.
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