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NYY-6a

Chemical Structure : NYY-6a

CAS No.: 3116732-35-2

NYY-6a

Catalog No.: PC-28502Not For Human Use, Lab Use Only.

NYY-6a is a potent ferroptosis inhibitor, inhibits RSL3-induced ferroptosis with EC50 of 50 nM in 786-O cell line, functions as a radical trapping antioxidant, alleviates ferroptosis-related acute liver injury in vivo.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

NYY-6a is a potent ferroptosis inhibitor, inhibits RSL3-induced ferroptosis with EC50 of 50 nM in 786-O cell line, functions as a radical trapping antioxidant, alleviates ferroptosis-related acute liver injury in vivo.

Physicochemical Properties

M.Wt 374.44
Formula C23H22N2O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

benzyl (R)-(3-methyl-3-phenyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-yl)carbamate

References

1. Wan BW, et al. Bioorg Chem. 2025 Mar;156:108201.

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