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Chemical Structure : NaPi2b inhibitor 15
Catalog No.: PC-73331Not For Human Use, Lab Use Only.
NaPi2b inhibitor 15 is an orally administrable small-molecule NaPi2b (NaPi-2b, SLC34A2) inhibitor, inhibits phosphate uptake in vitro with IC50 of 64 nM.
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NaPi2b inhibitor 15 is an orally administrable small-molecule NaPi2b (NaPi-2b, SLC34A2) inhibitor, inhibits phosphate uptake in vitro with IC50 of 64 nM.
NaPi2b inhibitor 15 showed a low bioavailability (F = 0.1%) in rats and a reduction in phosphate absorption in the rat intestinal loop assay comparable to sevelamer hydrochloride.
| M.Wt | 943.470 | |
| Formula | C44H58ClF3N4O11S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Michihiro Maemoto, et al. J Med Chem. 2022 Feb 10;65(3):1946-1960.
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