Nacresertib

Chemical Structure : Nacresertib

Catalog No.: PC-24961Not For Human Use, Lab Use Only.

Nacresertib is a potent, selctive IRAK4 inhibitor with IC50 of 6.0 nM, >500-fold selective over IRAK1

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Biological Activity

Nacresertib is a potent, selctive IRAK4 inhibitor with IC50 of 6.0 nM, >500-fold selective over IRAK1.

M.Wt	410.47
Formula	C22H26N4O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Pyridinecarboxamide, N-[2-(trans-4-hydroxy-4-methylcyclohexyl)-6-methoxy-2H-indazol-5-yl]-6-methyl-, 1-oxide

1. Patent WO2021057785 A1 (Compound II).

2. Pantent CN113831320 A.