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Naloxonazine dihydrochloride

Chemical Structure : Naloxonazine dihydrochloride

CAS No.: 880759-65-9

Naloxonazine dihydrochloride

Catalog No.: PC-24995Not For Human Use, Lab Use Only.

Naloxonazine dihydrochloride is a potent, specific μ-opioid receptor (MOR) antagonist with IC50 of 5.4 nM, shows anti-leishmanial activity.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Naloxonazine dihydrochloride is a potent, specific μ-opioid receptor (MOR) antagonist with IC50 of 5.4 nM, shows anti-leishmanial activity.

Physicochemical Properties

M.Wt 723.69
Formula C38H42N4O6.2ClH
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-, [(5α)-4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-ylidene]hydrazone, dihydrochloride, (5α)-

References

1. Chien CC, et al. Toxicol Lett. 2012 Jul 7;212(1):61-5.

2. Hahn EF, et al. 1982 Sep 20-27;31(12-13):1385-8.

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