Naperiglipron | GLP-1R agonist | Probechem Biochemicals

Chemical Structure : Naperiglipron

CAS No.: 2572566-11-9

Catalog No.: PC-26342Not For Human Use, Lab Use Only.

Naperiglipron (LY3549492) is a highly potent Glucagon-like peptide 1 receptor (GLP-1R) agonist with EC50 of 1.14 nM for hGLP-1R.

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Biological Activity

Naperiglipron (LY3549492) is a highly potent Glucagon-like peptide 1 receptor (GLP-1R) agonist with EC50 of 1.14 nM for hGLP-1R.

M.Wt	580.59
Formula	C33H26F2N4O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-(4-(6-((4-Cyano-2-fluorobenzyl)oxy)pyridin-2-yl)-2-fluoro-5-methylbenzyl)-1-(oxetan-2-ylmethyl)-1H-benzo[d]imidazole-6-carboxylic acid

1. Patent WO2020263695A1.