Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-Nuclear Receptor/Transcription Factor-CREB/CBP-Naphthol AS-E
Naphthol AS-E

Chemical Structure : Naphthol AS-E

CAS No.: 92-78-4

Add to Favorites

Naphthol AS-E

Catalog No.: PC-61256Not For Human Use, Lab Use Only.

Naphthol AS-E is a cell-permeable inhibitor of the KIX-KID interaction and CREB-mediated gene transcription (IC50=2.26 uM).

Packing Price Stock Quantity
50 mg $88 In stock
100 mg $128 In stock
200 mg Get quote
1 g Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Naphthol AS-E is a cell-permeable inhibitor of the KIX-KID interaction and CREB-mediated gene transcription (IC50=2.26 uM).
Naphthol AS-E is the first KIX-binding small molecule to inhibit CREB-dependent gene transcription in living cells with IC50 in the low-uM range and a novel template for inhibiting protein-protein interactions.

Physicochemical Properties

M.Wt 297.738
Formula C17H12ClNO2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(4-chlorophenyl)-3-hydroxy-2-naphthamide

References

1. Jiang M, et al. J Med Chem. 2012 Apr 26;55(8):4020-4.

2. Li BX, et al. Chembiochem. 2009 Nov 23;10(17):2721-4.

3. Best JL, et al. Proc Natl Acad Sci U S A. 2004 Dec 21;101(51):17622-7.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: