Chemical Structure : Narlaprevir
CAS No.:
865466-24-6
Narlaprevir
(SCH900518, SCH-900518)
Catalog No. : PC-42515Not For Human Use, Lab Use Only.
Narlaprevir (SCH900518) is a potent, second generation HCV NS3 serine protease inhibitor with Ki of 6 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4251501
Biological Activity
Narlaprevir (SCH900518) is a potent, second generation HCV NS3 serine protease inhibitor with Ki of 6 nM.
Physicochemical Properties
M.Wt
707.9639
Formula
C36H61N5O7S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
3-Azabicyclo[3.1.0]hexane-2-carboxamide, N-[(1S)-1-[2-(cyclopropylamino)-2-oxoacetyl]pentyl]-3-[(2S)-2-[[[[1-[[(1,1-dimethylethyl)sulfonyl]methyl]cyclohexyl]amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]-6,6-dimethyl-, (1R,2S,5S)-
References
1. Arasappan A, et al. ACS Med Chem Lett.
2. Tong X, et al. Antimicrob Agents Chemother.
3. de Bruijne J, et al. Hepatology.
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