Navepdekinra | IL-17A inhibitor | Probechem Biochemicals

Chemical Structure : Navepdekinra

Catalog No.: PC-24963Not For Human Use, Lab Use Only.

Navepdekinra (DC-806, S 011806, LY4100504) is a potent, oral, next-generation interleukin-17A (IL-17A) inhibitor.

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Biological Activity

Navepdekinra (DC-806, S 011806, LY4100504) is a potent, oral, next-generation interleukin-17A (IL-17A) inhibitor.

M.Wt	625.79
Formula	C33H48FN7O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-ethyl-N-((S)-2-((2-fluoro-4-((2S,3R)-4-(4-methylpiperazin-1-yl)-4-oxo-3-propionamidobutan-2-yl)phenyl)amino)-1-((1r,4S)-4-methylcyclohexyl)-2-oxoethyl)-1H-pyrazole-5-carboxamide

1. Patent US20200247785 A1 (Example 210).

2. Dahyeon Kim, et al. Am J Clin Dermatol. 2025 May;26(3):307-320.