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Chemical Structure : Navoximod
CAS No.: 1402837-78-8
Catalog No.: PC-45552Not For Human Use, Lab Use Only.
Navoximod (GDC-0919, NLG-919) is a potent, selective inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1) with biochemical IC50 of 28 nM, and of Ki of 5.8 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $198 | In stock | |
| 10 mg | $298 | In stock | |
| 25 mg | $488 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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| M.Wt | 316.3699 | |
| Formula | C18H21FN2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: 100 mg/mL |
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| Chemical Name/SMILES |
5H-Imidazo[5,1-a]isoindole-5-ethanol, 6-fluoro-α-(trans-4-hydroxycyclohexyl)-, (αR,5S)- |
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1. Mautino, et al. Preparation of fused imidazole derivatives as IDO inhibitors. From PCT Int. Appl. (2012), 20121018.
2. Kumar S, et al. J Med Chem. 2019 Jul 25;62(14):6705-6733.
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