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Nedocromil

Chemical Structure : Nedocromil

CAS No.: 69049-73-6

Nedocromil (FPL 59002, FPL59002)

Catalog No.: PC-43540Not For Human Use, Lab Use Only.

Nedocromil (FPL59002) is a mast cell stabilizer, inhibits the degranulation of mast cells, prevents release of histamine and tryptase, so preventing the synthesis of prostaglandins and leukotrienes, including histamine, leukotriene C4 (LTC4), and prostaglandin D2 (PGD2).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Nedocromil (FPL59002) is a mast cell stabilizer, inhibits the degranulation of mast cells, prevents release of histamine and tryptase, so preventing the synthesis of prostaglandins and leukotrienes, including histamine, leukotriene C4 (LTC4), and prostaglandin D2 (PGD2).

Physicochemical Properties

M.Wt 371.3408
Formula C19H17NO7
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: 15 mg/mL

Chemical Name/SMILES

4H-Pyrano[3,2-g]quinoline-2,8-dicarboxylic acid, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-

References

1. Lal S, et al. Thorax. 1984 Nov;39(11):809-12.

2. Eady RP, et al. Br J Pharmacol. 1985 Jun;85(2):323-5.

3. Cairns H, et al. J Med Chem. 1985 Dec;28(12):1832-42.

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