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Chemical Structure : Negamycin
Catalog No.: PC-70301Not For Human Use, Lab Use Only.
Negamycin is a dipeptide antibiotic that inhibits the initiation of protein synthesis.
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Negamycin is a dipeptide antibiotic that inhibits the initiation of protein synthesis.
Negamycin also restores dystrophin expression in skeletal and cardiac muscles of the mdx mouse.
Negamycin interferes with decoding and translocation by simultaneous interaction with rRNA and tRNA.
| M.Wt | 248.283 | |
| Formula | C9H20N4O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Arakawa M, et al. J Biochem. 2003 Nov;134(5):751-8.
2. Polikanov YS, et al. Mol Cell. 2014 Nov 20;56(4):541-50.
3. Cocozaki AI, et al. Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8188-93.
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