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Chemical Structure : Nelfinavir mesylate
CAS No.: 159989-65-8
Catalog No.: PC-44304Not For Human Use, Lab Use Only.
Nelfinavir (AG-1343) mesylate is a potent and orally bioavailable HIV-1 protease inhibitor with Ki of 2 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $98 | In stock | |
| 10 mg | $158 | In stock | |
| 50 mg | $328 | In stock | |
| 100 mg | Get quote |
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Nelfinavir (AG-1343) mesylate is a potent and orally bioavailable HIV-1 protease inhibitor with Ki of 2 nM.
Nelfinavir (AG-1343) exhibits an antiviral EC50 of 30 nM in HIV-1 strain RF-infected CEM-SS cells.
Nelfinavir (AG-1343) also inhibits the proliferation of NSCLC cells, as well as every cell line in the NCI60 cell line panel with mean GI50 of 5.2 uM, induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo.
| M.Wt | 663.8881 | |
| Formula | C33H49N3O7S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
3-Isoquinolinecarboxamide, N-(1,1-dimethylethyl)decahydro-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylthio)butyl]-, (3S,4aS,8aS)-, methanesulfonate (1:1) |
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1. Zhang KE, et al. Antimicrob Agents Chemother. 2001 Apr;45(4):1086-93.
2. Shetty BV, et al. Antimicrob Agents Chemother. 1996 Jan;40(1):110-4.
3. Gills JJ, et al. Clin Cancer Res. 2007 Sep 1;13(17):5183-94.
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