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Chemical Structure : Nelociguat
CAS No.: 625115-52-8
Catalog No.: PC-45991Not For Human Use, Lab Use Only.
Nelociguat (BAY60-4552) is a direct soluble guanylate cyclase (sGC) stimulator that acts independently of nitric oxide (NO).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $128 | In stock | |
| 25 mg | $218 | In stock | |
| 50 mg | $358 | In stock | |
| 100 mg | Get quote |
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Nelociguat (BAY60-4552) is a direct soluble guanylate cyclase (sGC) stimulator that acts independently of nitric oxide (NO).
Nelociguat (BAY60-4552) has an EC50 of 353 nM on P-VASP formation in rat aortic smooth muscle cells.
| M.Wt | 408.3891 | |
| Formula | C19H17FN8O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 105 mg/mL (Need ultrasonic) |
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| Chemical Name/SMILES |
Carbamic acid, N-[4,6-diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-, methyl ester |
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1. Costell MH, et al. Front Pharmacol. 2012 Jul 5;3:128.
2. Oudot A, et al. Eur Urol. 2011 Nov;60(5):1020-6.
3. Albersen M, et al. J Sex Med. 2013 May;10(5):1268-77.
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