Neutrophil elastase inhibitor PD05 | Neutrophil elastase inhibitor

Chemical Structure : Neutrophil elastase inhibitor PD05

Neutrophil elastase inhibitor PD05 (PD05)

Catalog No.: PC-49231Not For Human Use, Lab Use Only.

Neutrophil elastase inhibitor PD05 is a potent selective and reversible human neutrophil elastase (HNE) inhibitor with Kd of 1.63 nM.

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Biological Activity

Neutrophil elastase inhibitor PD05 is a potent selective and reversible human neutrophil elastase (HNE) inhibitor with Kd of 1.63 nM.
Neutrophil elastase inhibitor PD05 reduces the alveolar collapse induced by neutrophil elastase in mouse model of COPD.

Physicochemical Properties

M.Wt	225.628
Formula	C10H8ClNO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(1-chloroethoxy)-4H-benzo[d][1,3]oxazin-4-one

References

1. Sayantan Sengupta, et al. Eur J Pharmacol. 2022 Aug 8;931:175187.

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Neutrophil elastase inhibitor PD05 (PD05)

Biological Activity

Physicochemical Properties

References

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