Nexturastat A |CAS:1403783-31-2 Probechem Biochemicals

Chemical Structure : Nexturastat A

CAS No.: 1403783-31-2

Nexturastat A (HDAC6 inhibitor)

Catalog No.: PC-45044Not For Human Use, Lab Use Only.

Nexturastat A is a potent and selective HDAC6 inhibitor with IC50 of 5 nM.

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5 mg	$158	In stock
10 mg	$248	In stock
25 mg	$398	In stock
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Biological Activity

Nexturastat A is a potent and selective HDAC6 inhibitor with IC50 of 5 nM.
Nexturastat A displays >100-fold selectivity over other HDAC isozymes (600-fold relative to the inhibition of HDAC1).

Physicochemical Properties

M.Wt	341.4042
Formula	C19H23N3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: ≥ 56 mg/mL
Chemical Name/SMILES	Benzamide, 4-[[butyl[(phenylamino)carbonyl]amino]methyl]-N-hydroxy-

References

1. Bergman JA, et al. J Med Chem. 2012 Nov 26;55(22):9891-9.

2. Miyake Y, et al. Nat Chem Biol. 2016 Sep;12(9):748-54.

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Nexturastat A (HDAC6 inhibitor)

Biological Activity

Physicochemical Properties

References

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