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Nexturastat A

Chemical Structure : Nexturastat A

CAS No.: 1403783-31-2

Nexturastat A (HDAC6 inhibitor)

Catalog No.: PC-45044Not For Human Use, Lab Use Only.

Nexturastat A is a potent and selective HDAC6 inhibitor with IC50 of 5 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Nexturastat A is a potent and selective HDAC6 inhibitor with IC50 of 5 nM.
Nexturastat A displays >100-fold selectivity over other HDAC isozymes (600-fold relative to the inhibition of HDAC1).

Physicochemical Properties

M.Wt 341.4042
Formula C19H23N3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 56 mg/mL

Chemical Name/SMILES

Benzamide, 4-[[butyl[(phenylamino)carbonyl]amino]methyl]-N-hydroxy-

References

1. Bergman JA, et al. J Med Chem. 2012 Nov 26;55(22):9891-9.

2. Miyake Y, et al. Nat Chem Biol. 2016 Sep;12(9):748-54.

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