Niclosamide | STAT3 inhibitor | Probechem Biochemicals

Chemical Structure : Niclosamide

CAS No.: 50-65-7

Catalog No.: PC-24028Not For Human Use, Lab Use Only.

Niclosamide (BAY2353) is an orally active antihelminthic agent, also is a STAT3 inhibitor with IC50 of 0.25 uM in HeLa cells.

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Biological Activity

Niclosamide (BAY2353) is an orally active antihelminthic agent, also is a STAT3 inhibitor with IC50 of 0.25 uM in HeLa cells.

M.Wt	327.12
Formula	C13H8Cl2N2O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide

1. Xiaomei Ren, et al. ACS Med Chem Lett. 2010 Sep 7;1(9):454-9.

2. P Andrews, et al. Pharmacol Ther. 1982;19(2):245-95.

3. Kei Satoh, et al.Clin Cancer Res. 2016 Jul 15;22(14):3458-66.