Catalog No.: PC-42123Not For Human Use, Lab Use Only.
Nigericin sodium (NSC 292567) is an ionophore antibiotic derived from S. hygroscopicus that acts as a potassium ionophore promoting K+/H+ exchange across mitochondrial membranes.
Nigericin sodium (NSC 292567) is an ionophore antibiotic derived from S. hygroscopicus that acts as a potassium ionophore promoting K+/H+ exchange across mitochondrial membranes.
Nigericin sodium is a research tool to disrupt intracellular H+ and K+ concentration, thus altering pH, membrane potential, and cell volum。
Nigericin sodium inhibits the Golgi functions in Eukaryotic cells.
Nigericin sodium is the canonical NLRP3 inflammasome agonist.
Physicochemical Properties
M.Wt
746.9432
Formula
C40H67NaO11
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in ethanol; DMSO: < 0.3 mg/mL; H2O: < 0.3 mg/mL
