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Nisotirostide

Chemical Structure : Nisotirostide

CAS No.: 2663844-45-7

Nisotirostide (LY-3457263, LY3457263)

Catalog No.: PC-23085Not For Human Use, Lab Use Only.

Nisotirotide (LY-3457263) is a gut hormone peptide YY (PYY) analog and Neuropeptide Y receptor (NPY receptor) agonist.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Nisotirotide (LY-3457263) is a gut hormone peptide YY (PYY) analog and Neuropeptide Y receptor (NPY receptor) agonist.

Physicochemical Properties

M.Wt 4974.53
Formula C230H343N59O65
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Chain1:Pro-Lys-Pro-Glu-Lys-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Trp-Gln-Arg-Tyr-Tyr-Ala-Glu-Leu-Arg-His-Tyr-Leu-Asn-Trp-Leu-Thr-Arg-Gln-Arg-Tyr-NH2
Chain2:Ggu-Ggu-Oaa (Amide bridge:Chain1 Lys5-Chain2 Oaa3)

References

1. Kloock S, et al. Pharmacol Ther. 2023 Nov;251:108549.

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