Noraramtide | CAS 2580150-96-3 | Probechem Biochemicals

Chemical Structure : Noraramtide

Noraramtide (BHV-1100, BHV1100, KP1237)

Catalog No.: PC-28245Not For Human Use, Lab Use Only.

Noraramtide (BHV-1100) is a novel Antibody Recruiting Molecule (ARM), engages CD38 on MM cells and CD16 (via IgG) on natural killer (NK) cells to promote antibody-dependent cell cytotoxicity (ADCC) without NK fratricide.

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Biological Activity

Physicochemical Properties

M.Wt	4633.11
Formula	C210H300N48O65S3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Ala-Arg-{2-aminoheptanoicacid}-Tyr-His-Asp-Gly-Val-Leu-{Phe(4-phenyl)}-{2-aminoheptanoicacid}-{d-Cys(s-carboxymethyl)}-{XGly}-{γGlu}-{γGlu}-{d-γGlu}-{γGlu}-{γGlu}-Gly-Gly-Asp-Cys-Ala-Trp-His-Leu-Gly-Glu-Leu-Val-Trp-Cys-Thr (Sulfidebridge:Ala1-Cys13,Disulfidebridge:Cys24-Cys34) X= NH2-PEG6-((6S)-1,4,5,5a,6,6a,7,8-octahydrocyclopropa[5,6]cycloocta[1,2-d][1,2,3]triazol-6-yl)methyl hydrogen carbonate-piperidine-4-carboxylic acid

References

1. Grace Caroline Birch PhD, et al. Cellular Immunotherapies, 10.1182/blood-2023-180224.

Noraramtide (BHV-1100, BHV1100, KP1237)

Biological Activity

Physicochemical Properties

References

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