Norendoxifen

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Chemical Structure : Norendoxifen

Catalog No.: PC-70132Not For Human Use, Lab Use Only.

Norendoxifen is an active metabolite of the selective estrogen receptor modulator (SERM) tamoxifen.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Norendoxifen is an active metabolite of the selective estrogen receptor modulator (SERM) tamoxifen.
Norendoxifen is not a SERM, and instead has been found to act as a potent and selective competitive inhibitor of aromatase with Ki of 35 nM.

Physicochemical Properties

M.Wt	359.47
Formula	C24H25NO2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(Z)-4-(1-(4-(2-aminoethoxy)phenyl)-2-phenylbut-1-en-1-yl)phenol

References

1. Lu WJ, et al. Breast Cancer Res Treat. 2012 May;133(1):99-109.

2. Lv W, et al. J Med Chem. 2015 Mar 26;58(6):2623-48.

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Norendoxifen

Biological Activity

Physicochemical Properties

References

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