Notum covalent inhibitor 2

Chemical Structure : Notum covalent inhibitor 2

Catalog No.: PC-72825Not For Human Use, Lab Use Only.

Notum covalent inhibitor 2 is a potent, covalent Notum inhibitor with IC50 of 12 nM in OPTS assays, more poent than Notum covalent inhibitor 1.

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Biological Activity

Notum covalent inhibitor 2 is a potent, covalent Notum inhibitor with IC50 of 12 nM in OPTS assays, more poent than Notum covalent inhibitor 1.

M.Wt	283.275
Formula	C14H15F2NO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2,2-difluoroethyl 4-(indolin-1-yl)-4-oxobutanoate

1. Zhao Y, et al. J Med Chem. 2021 Aug 12;64(15):11354-11363.