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Chemical Structure : Notum inhibitor 4d
Catalog No.: PC-72822Not For Human Use, Lab Use Only.
Notum inhibitor 4d is a highly potent inhibitor of Notum with IC50 of <10 nM, restores Wnt/β-catenin signaling in cell-based models.
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Notum inhibitor 4d is a highly potent inhibitor of Notum with IC50 of <10 nM, restores Wnt/β-catenin signaling in cell-based models.
Notum is a negative regulator of Wnt signaling acting through the hydrolysis of a palmitoleoylate ester, which is required for Wnt activity.
| M.Wt | 258.299 | |
| Formula | C12H10N4OS | |
| Appearance | Solid | |
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1. Steadman D, et al. J Med Chem. 2022 Jan 13;65(1):562-578.
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