Nur77 modulator 1 | Nur77 modulator | Probechem Biochemicals

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Chemical Structure : Nur77 modulator 1

CAS No.: 2469975-55-9

Nur77 modulator 1 (Compound10g)

Catalog No.: PC-26966Not For Human Use, Lab Use Only.

Nur77 modulator 1 is a high affintiy Nur77 modulator (KD = 3.58 uM), up-regulates Nur77 expression, mediates sub-cellular localization of Nur77, induces Nur77-dependent ER stress and autophagy, and results in cell apoptosis, shows broad-spectrum antiproliferative activity against hepatoma cells with IC50 of >2.0 uM.

Packing	Price	Stock
5 mg	$188	In stock
10 mg	$288	In stock
25 mg	$498	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Physicochemical Properties

M.Wt	495.60
Formula	C28H25N5O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-5-((8-Methoxy-2-methylquinolin-4-yl)amino)-N'-(4-(methylthio)benzylidene)-1H-indole-2-carbohydrazide

References

1. Baicun Li, et al. Eur J Med Chem. 2020 Oct 15;204:112608.

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Nur77 modulator 1 (Compound10g)

Biological Activity

Physicochemical Properties

References

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