Catalog No.: PC-35196Not For Human Use, Lab Use Only.
O-1602 (O1602) is an atypical cannabinoid, potent and selective agonist of GPR55 cannabinoid receptor with EC50 of 13 nM, shows no significant activity for CB1 and CB2 receptors (EC50>30 uM).
O-1602 (O1602) is an atypical cannabinoid, potent and selective agonist of GPR55 cannabinoid receptor with EC50 of 13 nM, shows no significant activity for CB1 and CB2 receptors (EC50>30 uM).
O-1602 stimulates GPR55-dependent GTPgammaS activity with EC50 of <2 nM.
O-1602 inhibits mouse osteoclast formation in vitro, stimulates mouse and human osteoclast polarization and resorption in vitro and caused activation of Rho and ERK1/2, affects bone mass in vivo.
O-1602 protects against experimental colitis and inhibits neutrophil recruitment.
