Catalog No.: PC-43282Not For Human Use, Lab Use Only.
Oct4-activating compound 2 (OAC2) is a small molecule Oct4-activating compound, enhances the iPSC reprogramming efficiency and accelerates the reprogramming process.
Oct4-activating compound 2 (OAC2) is a small molecule Oct4-activating compound, enhances the iPSC reprogramming efficiency and accelerates the reprogramming process.
OAC2 activates Oct4 and Nanog promoter-driven reporters in triplicate luciferase reporter assays, activates endogenous Oct4, Nanog, Sox2, and Tet1 expression.
OAC2 enhances reprogramming about fourfold at day 8 at 1 uM in iSF1 for the generation of mouse iPSCs.
Physicochemical Properties
M.Wt
236.2686
Formula
C15H12N2O
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 2.4 mg/mL
Chemical Name/SMILES
Benzamide, N-1H-indol-5-yl-
References
1. Li W, et al. Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):20853-8.
