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Chemical Structure : ODQ
CAS No.: 41443-28-1
Catalog No.: PC-63138Not For Human Use, Lab Use Only.
ODQ (sGC inhibitor ODQ) is a potent, selective, irreversible inhibitor of sGC (soluble guanylyl cyclase).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $128 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | $298 | In stock | |
| 100 mg | Get quote |
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ODQ (sGC inhibitor ODQ) is a potent, selective, irreversible inhibitor of sGC (soluble guanylyl cyclase).
ODQ inhibits the elevation of cGMP induced by the NO donor S-nitroso-DL-penicillamine in human platelets and rat vascular smooth muscle (IC50 = 10-60 nM and <10 nM, respectively).
ODQ has no effect on NO synthase.
| M.Wt | 187.158 | |
| Formula | C9H5N3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
1H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one |
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1. Moro MA, et al. Proc Natl Acad Sci U S A. 1996 Feb 20;93(4):1480-5.
2. Cellek S, et al. Br J Pharmacol. 1996 May;118(1):137-40.
3. Schrammel A, et al. Mol Pharmacol. 1996 Jul;50(1):1-5.
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